Compile Data Set for Download or QSAR
Found 77 of ic50 data for polymerid = 50007077
TargetCytochrome P450 26B1(Homo sapiens (Human))
University of Washington at Seattle

LigandPNGBDBM50253810(CHEMBL459505 | N-(4-(2-ethyl-1-(1H-1,2,4-triazol-1...)copy SMILEScopy InChI
Affinity DataIC50: 0.460nMAssay Description:Eighteen compounds were tested as potential inhibitors of CYP26A1 and CYP26B1. The formation of 9-cis-4-OH-RA metabolite was monitored and the percen...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2FN18J2US Patent
TargetCytochrome P450 26B1(Homo sapiens (Human))
University of Washington at Seattle

LigandPNGBDBM50253810(CHEMBL459505 | N-(4-(2-ethyl-1-(1H-1,2,4-triazol-1...)copy SMILEScopy InChI
Affinity DataIC50: 0.460nMAssay Description:Inhibition of microsomal fraction of human CYP26B1 expressed in Sf9 cells using 9-cis-RA as substrate preincubated for 5 mins followed by NADPH addit...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J38VG8PubMed
TargetCytochrome P450 26B1(Homo sapiens (Human))
University of Washington at Seattle

LigandPNGBDBM393281(US9963439, R116010)copy SMILEScopy InChI
Affinity DataIC50: 3.10nMAssay Description:Eighteen compounds were tested as potential inhibitors of CYP26A1 and CYP26B1. The formation of 9-cis-4-OH-RA metabolite was monitored and the percen...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2FN18J2US Patent
TargetCytochrome P450 26B1(Homo sapiens (Human))
University of Washington at Seattle

LigandPNGBDBM50157605(Liarozole | Liazal | R-75251 | US9963439, Liarozol...)copy SMILEScopy InChI
Affinity DataIC50: 18nMAssay Description:Eighteen compounds were tested as potential inhibitors of CYP26A1 and CYP26B1. The formation of 9-cis-4-OH-RA metabolite was monitored and the percen...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2FN18J2US Patent
TargetCytochrome P450 26B1(Homo sapiens (Human))
University of Washington at Seattle

LigandPNGBDBM50157605(Liarozole | Liazal | R-75251 | US9963439, Liarozol...)copy SMILEScopy InChI
Affinity DataIC50: 18nMAssay Description:Inhibition of microsomal fraction of human CYP26B1 expressed in Sf9 cells using 9-cis-RA as substrate preincubated for 5 mins followed by NADPH addit...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J38VG8PubMed
TargetCytochrome P450 26B1(Homo sapiens (Human))
University of Washington at Seattle

LigandPNGBDBM151585(US11739089, Compound Ketoconazole | US8987315, Ket...)copy SMILEScopy InChI
Affinity DataIC50: 140nMAssay Description:Eighteen compounds were tested as potential inhibitors of CYP26A1 and CYP26B1. The formation of 9-cis-4-OH-RA metabolite was monitored and the percen...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2FN18J2US Patent
TargetCytochrome P450 26B1(Homo sapiens (Human))
University of Washington at Seattle

LigandPNGBDBM557292(US11358933, Compound 026)copy SMILES
Affinity DataIC50: 200nMAssay Description:CYP26 inhibitory activities of various compounds.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2CC13XJUS Patent
TargetCytochrome P450 26B1(Homo sapiens (Human))
University of Washington at Seattle

LigandPNGBDBM476235(US10874634, Cmpd No. 17 | US11364220, Compound 17)copy SMILEScopy InChI
Affinity DataIC50: 290nMAssay Description:This retinoid activity assay measures the ability of test compounds to induce expression of a transiently transfected RA sensitive reporter construct...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2QN6B03US Patent
TargetCytochrome P450 26B1(Homo sapiens (Human))
University of Washington at Seattle

LigandPNGBDBM476235(US10874634, Cmpd No. 17 | US11364220, Compound 17)copy SMILEScopy InChI
Affinity DataIC50: 290nMAssay Description:CYP26A1 or CYP26B1 stably transfected HeLa cells were maintained in Minimum Essential Medium (MEM) containing 10% fetal bovine serum (FBS) and 100 &#...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2Q52SP3US Patent
TargetCytochrome P450 26B1(Homo sapiens (Human))
University of Washington at Seattle

LigandPNGBDBM557299(US11358933, Compound 034)copy SMILES
Affinity DataIC50: 500nMAssay Description:CYP26 inhibitory activities of various compounds.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2CC13XJUS Patent
TargetCytochrome P450 26B1(Homo sapiens (Human))
University of Washington at Seattle

LigandPNGBDBM31886(CD564 | CHEMBL309282)copy SMILEScopy InChI
Affinity DataIC50: 520nMAssay Description:Inhibition of microsomal fraction of human CYP26B1 expressed in Sf9 cells using 9-cis-RA as substrate preincubated for 5 mins followed by NADPH addit...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J38VG8PubMed
TargetCytochrome P450 26B1(Homo sapiens (Human))
University of Washington at Seattle

LigandPNGBDBM476228(US10874634, Cmpd No. 10 | US11364220, Compound 10)copy SMILEScopy InChI
Affinity DataIC50: 550nMAssay Description:CYP26A1 or CYP26B1 stably transfected HeLa cells were maintained in Minimum Essential Medium (MEM) containing 10% fetal bovine serum (FBS) and 100 &#...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2Q52SP3US Patent
TargetCytochrome P450 26B1(Homo sapiens (Human))
University of Washington at Seattle

LigandPNGBDBM476228(US10874634, Cmpd No. 10 | US11364220, Compound 10)copy SMILEScopy InChI
Affinity DataIC50: 550nMAssay Description:This retinoid activity assay measures the ability of test compounds to induce expression of a transiently transfected RA sensitive reporter construct...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2QN6B03US Patent
TargetCytochrome P450 26B1(Homo sapiens (Human))
University of Washington at Seattle

LigandPNGBDBM50157722(CHEMBL3787323)copy SMILEScopy InChI
Affinity DataIC50: 680nMAssay Description:Inhibition of microsomal fraction of human CYP26B1 expressed in Sf9 cells using 9-cis-RA as substrate preincubated for 5 mins followed by NADPH addit...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J38VG8PubMed
TargetCytochrome P450 26B1(Homo sapiens (Human))
University of Washington at Seattle

LigandPNGBDBM50157724(CHEMBL3787564 | US9963439, Compound B)copy SMILEScopy InChI
Affinity DataIC50: 930nMAssay Description:Inhibition of microsomal fraction of human CYP26B1 expressed in Sf9 cells using 9-cis-RA as substrate preincubated for 5 mins followed by NADPH addit...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J38VG8PubMed
TargetCytochrome P450 26B1(Homo sapiens (Human))
University of Washington at Seattle

LigandPNGBDBM50157727(CHEMBL3786184)copy SMILEScopy InChI
Affinity DataIC50: 1.03E+3nMAssay Description:Inhibition of microsomal fraction of human CYP26B1 expressed in Sf9 cells using 9-cis-RA as substrate preincubated for 5 mins followed by NADPH addit...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J38VG8PubMed
TargetCytochrome P450 26B1(Homo sapiens (Human))
University of Washington at Seattle

LigandPNGBDBM50157721(CHEMBL3786620)copy SMILEScopy InChI
Affinity DataIC50: 1.03E+3nMAssay Description:Inhibition of microsomal fraction of human CYP26B1 expressed in Sf9 cells using 9-cis-RA as substrate preincubated for 5 mins followed by NADPH addit...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J38VG8PubMed
TargetCytochrome P450 26B1(Homo sapiens (Human))
University of Washington at Seattle

LigandPNGBDBM50033067(4-[2-(5,5,8,8-Tetramethyl-5,6,7,8-tetrahydro-napht...)copy SMILEScopy InChI
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of microsomal fraction of human CYP26B1 expressed in Sf9 cells using 9-cis-RA as substrate preincubated for 5 mins followed by NADPH addit...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J38VG8PubMed
TargetCytochrome P450 26B1(Homo sapiens (Human))
University of Washington at Seattle

LigandPNGBDBM50157729(CHEMBL3787691)copy SMILEScopy InChI
Affinity DataIC50: 1.40E+3nMAssay Description:Inhibition of microsomal fraction of human CYP26B1 expressed in Sf9 cells using 9-cis-RA as substrate preincubated for 5 mins followed by NADPH addit...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J38VG8PubMed
TargetCytochrome P450 26B1(Homo sapiens (Human))
University of Washington at Seattle

LigandPNGBDBM50157731(CHEMBL3785511 | US9963439, Compound C)copy SMILEScopy InChI
Affinity DataIC50: 1.40E+3nMAssay Description:Inhibition of microsomal fraction of human CYP26B1 expressed in Sf9 cells using 9-cis-RA as substrate preincubated for 5 mins followed by NADPH addit...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J38VG8PubMed
TargetCytochrome P450 26B1(Homo sapiens (Human))
University of Washington at Seattle

LigandPNGBDBM50157604(CHEMBL3786324)copy SMILEScopy InChI
Affinity DataIC50: 1.70E+3nMAssay Description:Inhibition of microsomal fraction of human CYP26B1 expressed in Sf9 cells using 9-cis-RA as substrate preincubated for 5 mins followed by NADPH addit...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J38VG8PubMed
TargetCytochrome P450 26B1(Homo sapiens (Human))
University of Washington at Seattle

LigandPNGBDBM476180(US10874634, Cmpd No. 02 | US11364220, Compound 02)copy SMILEScopy InChI
Affinity DataIC50: 2.06E+3nMAssay Description:CYP26A1 or CYP26B1 stably transfected HeLa cells were maintained in Minimum Essential Medium (MEM) containing 10% fetal bovine serum (FBS) and 100 &#...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2Q52SP3US Patent
TargetCytochrome P450 26B1(Homo sapiens (Human))
University of Washington at Seattle

LigandPNGBDBM476180(US10874634, Cmpd No. 02 | US11364220, Compound 02)copy SMILEScopy InChI
Affinity DataIC50: 2.06E+3nMAssay Description:This retinoid activity assay measures the ability of test compounds to induce expression of a transiently transfected RA sensitive reporter construct...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2QN6B03US Patent
TargetCytochrome P450 26B1(Homo sapiens (Human))
University of Washington at Seattle

LigandPNGBDBM557298(US11358933, Compound 032)copy SMILES
Affinity DataIC50: 2.30E+3nMAssay Description:CYP26 inhibitory activities of various compounds.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2CC13XJUS Patent
TargetCytochrome P450 26B1(Homo sapiens (Human))
University of Washington at Seattle

LigandPNGBDBM50157718(CHEMBL3785701)copy SMILEScopy InChI
Affinity DataIC50: 4.40E+3nMAssay Description:Inhibition of microsomal fraction of human CYP26B1 expressed in Sf9 cells using 9-cis-RA as substrate preincubated for 5 mins followed by NADPH addit...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J38VG8PubMed
TargetCytochrome P450 26B1(Homo sapiens (Human))
University of Washington at Seattle

LigandPNGBDBM50157719(CHEMBL3785624)copy SMILEScopy InChI
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of microsomal fraction of human CYP26B1 expressed in Sf9 cells using 9-cis-RA as substrate preincubated for 5 mins followed by NADPH addit...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J38VG8PubMed
TargetCytochrome P450 26B1(Homo sapiens (Human))
University of Washington at Seattle

LigandPNGBDBM50157723(CHEMBL3786927)copy SMILEScopy InChI
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of microsomal fraction of human CYP26B1 expressed in Sf9 cells using 9-cis-RA as substrate preincubated for 5 mins followed by NADPH addit...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J38VG8PubMed
TargetCytochrome P450 26B1(Homo sapiens (Human))
University of Washington at Seattle

LigandPNGBDBM50157726(CHEMBL3786043)copy SMILEScopy InChI
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of microsomal fraction of human CYP26B1 expressed in Sf9 cells using 9-cis-RA as substrate preincubated for 5 mins followed by NADPH addit...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J38VG8PubMed
TargetCytochrome P450 26B1(Homo sapiens (Human))
University of Washington at Seattle

LigandPNGBDBM50157608(CHEMBL95949)copy SMILEScopy InChI
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of microsomal fraction of human CYP26B1 expressed in Sf9 cells using 9-cis-RA as substrate preincubated for 5 mins followed by NADPH addit...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J38VG8PubMed
TargetCytochrome P450 26B1(Homo sapiens (Human))
University of Washington at Seattle

LigandPNGBDBM50157730(CHEMBL3785557)copy SMILEScopy InChI
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of microsomal fraction of human CYP26B1 expressed in Sf9 cells using 9-cis-RA as substrate preincubated for 5 mins followed by NADPH addit...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J38VG8PubMed
TargetCytochrome P450 26B1(Homo sapiens (Human))
University of Washington at Seattle

LigandPNGBDBM50157728(CHEMBL3785761)copy SMILEScopy InChI
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of microsomal fraction of human CYP26B1 expressed in Sf9 cells using 9-cis-RA as substrate preincubated for 5 mins followed by NADPH addit...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J38VG8PubMed
TargetCytochrome P450 26B1(Homo sapiens (Human))
University of Washington at Seattle

LigandPNGBDBM50032675(4-[1-(3,5,5,8,8-pentamethyl-5,6,7,8-tetrahydronaph...)copy SMILEScopy InChI
Affinity DataIC50: 5.90E+3nMAssay Description:Inhibition of microsomal fraction of human CYP26B1 expressed in Sf9 cells using 9-cis-RA as substrate preincubated for 5 mins followed by NADPH addit...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J38VG8PubMed
TargetCytochrome P450 26B1(Homo sapiens (Human))
University of Washington at Seattle

LigandPNGBDBM50157720(CHEMBL3786340)copy SMILEScopy InChI
Affinity DataIC50: 6.20E+3nMAssay Description:Inhibition of microsomal fraction of human CYP26B1 expressed in Sf9 cells using 9-cis-RA as substrate preincubated for 5 mins followed by NADPH addit...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J38VG8PubMed
TargetCytochrome P450 26B1(Homo sapiens (Human))
University of Washington at Seattle

LigandPNGBDBM557293(US11358933, Compound 027)copy SMILES
Affinity DataIC50: 8.80E+3nMAssay Description:CYP26 inhibitory activities of various compounds.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2CC13XJUS Patent
TargetCytochrome P450 26B1(Homo sapiens (Human))
University of Washington at Seattle

LigandPNGBDBM476173(US10874634, Cmpd No. 01 | US11364220, Compound 01)copy SMILEScopy InChI
Affinity DataIC50: 8.81E+3nMAssay Description:This retinoid activity assay measures the ability of test compounds to induce expression of a transiently transfected RA sensitive reporter construct...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2QN6B03US Patent
TargetCytochrome P450 26B1(Homo sapiens (Human))
University of Washington at Seattle

LigandPNGBDBM476173(US10874634, Cmpd No. 01 | US11364220, Compound 01)copy SMILEScopy InChI
Affinity DataIC50: 8.81E+3nMAssay Description:CYP26A1 or CYP26B1 stably transfected HeLa cells were maintained in Minimum Essential Medium (MEM) containing 10% fetal bovine serum (FBS) and 100 &#...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2Q52SP3US Patent
TargetCytochrome P450 26B1(Homo sapiens (Human))
University of Washington at Seattle

LigandPNGBDBM476236(US10874634, Cmpd No. 18 | US11364220, Compound 18)copy SMILEScopy InChI
Affinity DataIC50: 9.07E+3nMAssay Description:This retinoid activity assay measures the ability of test compounds to induce expression of a transiently transfected RA sensitive reporter construct...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2QN6B03US Patent
TargetCytochrome P450 26B1(Homo sapiens (Human))
University of Washington at Seattle

LigandPNGBDBM476236(US10874634, Cmpd No. 18 | US11364220, Compound 18)copy SMILEScopy InChI
Affinity DataIC50: 9.07E+3nMAssay Description:CYP26A1 or CYP26B1 stably transfected HeLa cells were maintained in Minimum Essential Medium (MEM) containing 10% fetal bovine serum (FBS) and 100 &#...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2Q52SP3US Patent
TargetCytochrome P450 26B1(Homo sapiens (Human))
University of Washington at Seattle

LigandPNGBDBM50157717(CHEMBL3786581)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of microsomal fraction of human CYP26B1 expressed in Sf9 cells using 9-cis-RA as substrate preincubated for 5 mins followed by NADPH addit...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J38VG8PubMed
TargetCytochrome P450 26B1(Homo sapiens (Human))
University of Washington at Seattle

LigandPNGBDBM476222(US10874634, Cmpd No. 05 | US11364220, Compound 05)copy SMILEScopy InChI
Affinity DataIC50: 1.15E+4nMAssay Description:CYP26A1 or CYP26B1 stably transfected HeLa cells were maintained in Minimum Essential Medium (MEM) containing 10% fetal bovine serum (FBS) and 100 &#...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2Q52SP3US Patent
TargetCytochrome P450 26B1(Homo sapiens (Human))
University of Washington at Seattle

LigandPNGBDBM476222(US10874634, Cmpd No. 05 | US11364220, Compound 05)copy SMILEScopy InChI
Affinity DataIC50: 1.15E+4nMAssay Description:This retinoid activity assay measures the ability of test compounds to induce expression of a transiently transfected RA sensitive reporter construct...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2QN6B03US Patent
TargetCytochrome P450 26B1(Homo sapiens (Human))
University of Washington at Seattle

LigandPNGBDBM476234(US10874634, Cmpd No. 16 | US11364220, Compound 16)copy SMILEScopy InChI
Affinity DataIC50: 1.19E+4nMAssay Description:CYP26A1 or CYP26B1 stably transfected HeLa cells were maintained in Minimum Essential Medium (MEM) containing 10% fetal bovine serum (FBS) and 100 &#...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2Q52SP3US Patent
TargetCytochrome P450 26B1(Homo sapiens (Human))
University of Washington at Seattle

LigandPNGBDBM476234(US10874634, Cmpd No. 16 | US11364220, Compound 16)copy SMILEScopy InChI
Affinity DataIC50: 1.19E+4nMAssay Description:This retinoid activity assay measures the ability of test compounds to induce expression of a transiently transfected RA sensitive reporter construct...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2QN6B03US Patent
TargetCytochrome P450 26B1(Homo sapiens (Human))
University of Washington at Seattle

LigandPNGBDBM50033077(4-[2-(5,5,8,8-Tetramethyl-5,6,7,8-tetrahydro-napht...)copy SMILEScopy InChI
Affinity DataIC50: 1.26E+4nMAssay Description:Inhibition of microsomal fraction of human CYP26B1 expressed in Sf9 cells using 9-cis-RA as substrate preincubated for 5 mins followed by NADPH addit...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J38VG8PubMed
TargetCytochrome P450 26B1(Homo sapiens (Human))
University of Washington at Seattle

LigandPNGBDBM476226(US10874634, Cmpd No. 09 | US11364220, Compound 09)copy SMILEScopy InChI
Affinity DataIC50: 1.42E+4nMAssay Description:This retinoid activity assay measures the ability of test compounds to induce expression of a transiently transfected RA sensitive reporter construct...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2QN6B03US Patent
TargetCytochrome P450 26B1(Homo sapiens (Human))
University of Washington at Seattle

LigandPNGBDBM476226(US10874634, Cmpd No. 09 | US11364220, Compound 09)copy SMILEScopy InChI
Affinity DataIC50: 1.42E+4nMAssay Description:CYP26A1 or CYP26B1 stably transfected HeLa cells were maintained in Minimum Essential Medium (MEM) containing 10% fetal bovine serum (FBS) and 100 &#...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2Q52SP3US Patent
TargetCytochrome P450 26B1(Homo sapiens (Human))
University of Washington at Seattle

LigandPNGBDBM50157611(CHEMBL3787627)copy SMILEScopy InChI
Affinity DataIC50: 1.45E+4nMAssay Description:Inhibition of microsomal fraction of human CYP26B1 expressed in Sf9 cells using 9-cis-RA as substrate preincubated for 5 mins followed by NADPH addit...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J38VG8PubMed
TargetCytochrome P450 26B1(Homo sapiens (Human))
University of Washington at Seattle

LigandPNGBDBM557291(US11358933, Compound 025)copy SMILES
Affinity DataIC50: 1.79E+4nMAssay Description:CYP26 inhibitory activities of various compounds.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2CC13XJUS Patent
TargetCytochrome P450 26B1(Homo sapiens (Human))
University of Washington at Seattle

LigandPNGBDBM557297(US11358933, Compound 031)copy SMILES
Affinity DataIC50: 1.83E+4nMAssay Description:CYP26 inhibitory activities of various compounds.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2CC13XJUS Patent
TargetCytochrome P450 26B1(Homo sapiens (Human))
University of Washington at Seattle

LigandPNGBDBM476217(US10874634, Cmpd No. 04 | US11364220, Compound 04)copy SMILEScopy InChI
Affinity DataIC50: 1.89E+4nMAssay Description:CYP26A1 or CYP26B1 stably transfected HeLa cells were maintained in Minimum Essential Medium (MEM) containing 10% fetal bovine serum (FBS) and 100 &#...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2Q52SP3US Patent
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